You should tell your doctor if any of the following side effects become severe or do not go away:

• Stomach pain
• Headache
• Constipation
• Vomiting
• Sweating
• Difficulty falling asleep or staying asleep

You should also contact your doctor immediately if you experience any of the following serious side effects:

• Itching, skin rash, or hives
• Difficulty breathing or slowed breathing
• Difficulty swallowing
• Upset stomach
• Unusual bleeding or bruising
• Extreme fatigue
• Loss of appetite
• Low energy
• Flu-like symptoms
• Pain in the upper right part of the stomach
• Yellowing of the skin or eyes

How should I use this medication?

This medication must be prescribed by a qualified doctor who meets specific requirements regarding the use of the medication. The dose of this medication varies depending on the individual situation and will be adjusted by your doctor.

The usual recommended starting dose is 4 mg to 8 mg (of buprenorphine) once daily. Your doctor will adjust the dose until you are no longer experiencing the effects of narcotic withdrawal. The maximum daily dose is 24 mg. Over time, your doctor may gradually decrease your dose until the medication has been stopped. Do not try to adjust the dose or stop the medication on your own.

The medication should be placed under the tongue until it has dissolved (this usually happens within 2 to 10 minutes). Do not swallow the tablets. Do not cut, break, crush or chew the tablets. If more than one tablet is needed at a time, both tablets may be placed under the tongue at the same time. Alternatively, you may place one tablet under the tongue at a time, placing the second tablet under the tongue immediately after the first tablet has dissolved.

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