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Bromazepam belongs to a class of medications called benzodiazepines. Bromazepam is used for short-term relief of excessive anxiety symptoms. It reduces anxiety by acting on certain brain chemicals called neurotransmitters.

It is used for treatments or in case of appearance of the following symptoms:

• Generalized anxiety;
• Mental disorders and behaviour related to alcohol use: withdrawal syndrome;
• Mental disorders and behaviour related to alcohol use: withdrawal syndrome with delirium;

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Bromazepam 3 mg | Dosage

The recommended starting dose of bromazepam for an adult ranges from 6 mg to 18 mg per day, taken in divided doses. The doctor may gradually increase the dose depending on the drug’s effectiveness and any side effects that occur. Generally, the maximum dose of bromazepam for adults is 30 mg daily, taken in divided doses. It is important that the dose is individualized to individual needs to avoid excessive sedation or motor impairment. Generally, the elderly are more sensitive to benzodiazepines and require lower doses.

The duration of treatment should not exceed one week, unless the doctor decides otherwise after this period. Bromazepam is usually used for a short time or as needed. It can cause dependence if taken for long periods. If you have been taking this medication regularly for a while (e.g., more than a month), do not stop taking it without first talking to your doctor. To avoid withdrawal effects, a gradual dose reduction is recommended before stopping.

Several factors can be taken into account when determining the dosage a person needs: their weight, their health condition, and whether they are taking other medications. If your doctor has recommended a different dosage than the one listed here, do not change how you take the medication without consulting them first.

Bromazepam 3mg | Usual dosage

This medication can be taken during or after meals. The tablets are divisible into 4, allowing the daily dose to be divided into several doses.

Adults:  6 mg per day, usually divided into 1/4 tablet in the morning, 1/4 tablet before lunch, and 1/2 tablet in the evening. The dosage may be increased to 18 mg per day in certain severe cases. The minimum effective dose is always sought.

In what cases is this medicine not recommended?

Avoid using bromazepam in the following circumstances:

• an allergy to bromazepam or any of the ingredients of the medicine;
• An allergy to another benzodiazepine;
• sleep apnea;
• closed angle glaucoma;
• a serious liver disease;
• severe respiratory disorders;
• A serious myasthenia.

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• constipation;
• rash;
• dizziness or a light-headed feeling;
• clumsiness or instability;
• headache;
• nausea;
• delayed reactions;
• drowsiness;
• tremors;
• speech disorders;
• Blurry vision.

Ask your doctor as soon as possible if any of the following side effects occur:

• tension;
• nightmares or sleep disturbances;
• fall;
• confusion;
• Dips or lightheadedness when moving from a lying position or sitting to a standing position;
• fractures;
• Hallucinations (the perception of phenomena that do not really exist);
  Changes in behavior (e.g., aggressiveness, agitation, a complex combination, a state of nervousness or irritability);
• a loss of memory of recent events;
• urinary problems (leaking, urgent need to urinate);
• Signs of depression (e.g., lack of concentration, weight fluctuations, sleep disturbances, disinterest in many activities, thoughts of suicide);
• Withdrawal symptoms after stopping the medication (e.g., DEA headache, convulsions, an extreme state of anxiety, sleep disturbances, a state of excitement, confusion, irritability).

Precautions for using bromazepam

Alcohol and other drugs that cause drowsiness

Since alcohol consumption is likely to decrease the effectiveness of this medication and increase the risk of side effects, people taking this medication should avoid consuming alcohol.

Do not combine this medication with other medications (e.g., antidepressants, sleeping pills, anti-anxiety medications) that cause drowsiness because there may be an additive effect of drowsiness and/or decreases in breathing that are likely to be life-threatening.

People with alcohol or drug dependence should not use Bromazepam except in rare cases and under medical supervision.

Falls and fractures

Bromazepam use can cause dizziness, lightheadedness, and loss of coordination. People taking this medication may be at increased risk of fractures. This is more likely to occur if the medication is taken by the elderly or by people who also use other drugs that cause drowsiness, including alcohol.

Dependency and weaning

Benzodiazepines such as bromazepam can lead to physical dependence (the need to take them regularly to avoid physical symptoms). Severe withdrawal symptoms (e.g., convulsive seizures) may occur if the dose is significantly reduced or treatment is suddenly discontinued.

These symptoms include irritability, nervousness, sleep disturbances, agitation, tremors, diarrhea, abdominal cramps, vomiting, memory loss, headache, muscle pain, extreme anxiety, tension, agitation, and confusion. Gradually reducing the dose under medical supervision can prevent or alleviate these withdrawal symptoms.

Depression

Like other benzodiazepines, bromazepam has been shown to cause mood changes and symptoms of depression. If you have depression or a history of depression, discuss with your doctor how this medication may affect your condition, how your condition may affect the administration and effectiveness of this medication, and the relevance of specific medical supervision.

If you experience symptoms of depression (such as difficulty concentrating, weight gain, sleep disturbances, or loss of interest in activities) or if you notice any symptoms associated with this medication, contact your doctor as soon as possible. Bromazepam is not recommended for people with depression or psychosis, or who have attempted suicide.

PREGNANCY

Bromazepam should not be used without medical advice during pregnancy. High doses in the last 6 months are not recommended. Late in pregnancy, even low-dose benzodiazepine treatment can cause adverse effects in the newborn. Medical supervision of the newborn is then necessary for 1 to 3 weeks, depending on the individual case.

This medicine passes into breast milk; breastfeeding is not recommended.